Life Sciences
AbiliLife
AbiliLife is developing a smart brace specifically designed for Parkinson’s patients with balance and postural instability. The brace will detect symptoms that lead to falls while providing comfort and support. AbiliLife is dedicated to improving the quality of life for Parkinson’s patients.
Accel Diagnostics
AccelDx is a medical device company developing pScreen™, a disruptive blood testing platform for the diagnosis and management of medical conditions in the Home/Point-of-Care setting. AccelDx’s solution enables physicians/patients to manage diseases in a timely and effective manner, thereby reducing cost and hospitalizations. AccelDx is currently focusing on pScreen-BNP™ for the in home daily monitoring of heart condition to prevent heart failure (HF) related re-hospitalizations: an untapped market opportunity of $1.9B.
ActivAided Orthotics (acquired by Elizur)
ActivAided Orthotics has developed a line of Postural Training Apparel to eliminate back pain by training self-corrective habits. By using the body’s own natural abilities, this wearable device addresses the root cause of back pain by teaching patients how to correct the harmful behaviors in their everyday activities. ActivAided’s first product RecoveryAid was found to decrease back pain in 90% of users, helping them return to their desired active lifestyles
Aethon, Inc. (acquired by ST Engineering)
Aethon is the leader in the business of low-cost, pilot-less hauling of materials indoors. We substitute a pilot-less Tug® for a person. Our competitive advantage is our patented indoor positioning system, with a manufacturing cost a fraction of our competitors, which navigates with ±3″ accuracy and allows us to automate indoor transport at one-fourth the cost of a person pushing a cart.
ALung Technologies, Inc.
ALung has developed the Hemolung™, an extracorporeal artificial lung that will replace or supplement the ventilator in the ICU for acute respiratory failure. The Hemolung will provide 50% of a patient’s respiratory need, allowing the lungs to heal, eliminating the need for intubation, sedation and mechanical ventilation. The Hemolung™ will reduce the incidence of ventilator associated pneumonia and hospital length of stay, resulting in a reduced cost of care for these patients. The Company has completed animal and human trials and expects initiate commercialization in Europe in Q1 2013.
Behaivior AI
Behaivior predicts and prevents addiction relapse using wearable devices and pattern detection algorithms.
BioHybrid Solutions, LLC.
BioHybrid Solutions™?world-renowned scientists are spearheading innovations in protein therapeutics by solving a problem facing the pharmaceutical industry: How can we create longer-lived, more effective medicine?
BIOSAFE, Inc. (acquired by Gelest)
BIOSAFE’s technology provides products with microbiological protection. Through a patented and EPA registered antimicrobial technology, products that include BIOSAFE are permanently protected bacteria, mold and mildew, algae, and even certain viruses. BIOSAFE works in close partnership with personnel from design and development and end-user marketing to insure simple integration and communication of strong product advantage.
Carmell Therapeutics Corporation
Carmell has developed a method of manufacturing biologically-active plastic materials from blood plasma. These plastics are sterile, off-the-shelf, easy to handle, shape and suture, have controlled degradation rates, contain known levels of bioactivity, and exhibit mechanical properties designed to match the repaired tissue. Carmell is focused on products for the sports medicine market with devices for the repair of tendon and cartilage injuries.
Cellumen, Inc. (Acquired by Apredica/Cyprotex)
Cellumen is the Systems Cell Biology company that is focused on delivering cellular models of disease and cytotoxicity that will revolutionize the drug discovery process and improve the quality of compounds entering clinical trials. The same systems cell biology approach is also being developed to optimize personalized medicine for clinical trials. Cellumen was acquired by Apredica/Cyprotex 8/4/10.
Circadiance LLC
Circadiance designs, makes and sells medical equipment. The company specializes in respiratory therapy including positive airway pressure, non-invasive ventilation and apnea monitoring. Our clinically proven, innovative solutions address patients ranging from premature newborns to frail elderly. Circadiance products deliver superior patient comfort and effectiveness in the acute care and home care settings, ultimately resulting in reduced cost of care and improved outcomes.
ClearCount Medical Solutions, Inc. (Acquired by a publicly-traded medical device company)
ClearCount Medical Solutions is a medical device company focused on patient safety solutions. ClearCount has assembled an extendable RFID-based platform that provides a comprehensive solution to improve efficiency while preventing medical errors. ClearCount’s SmartSponge®, SmartWand-DTX, and SmartSponge Flex systems are the only RFID-enabled systems for counting and detecting surgical sponges, thereby improving patient and Operating Room safety, enhancing productivity, and reducing cost. ClearCount has also advanced its proprietary RFID platform to include a unique on-metal RFID tag for surgical instrumentation tracking.
Cognition Therapeutics, Inc.
Cognition Therapuetics Inc. (CogRx) is a discovery and development pharmaceutical company focused on novel small molecule disease-modifying and symptomatic treatments for neurodegenerative disorders. Cognition Therapeutics has pioneered the discovery and development of new drugs acting at new targets to halt disease progression and improve symptoms in neurodegenerative disorders.
Cohera Medical, Inc.
Cohera Medical, Inc. is a medical device company that is developing a revolutionary line of surgical adhesives and wound management products. Cohera’s lead product under development, TissuGlu®, is an easy-to-use, resorbable adhesive that positions tissues for optimal healing while minimizing fluid accumulation. The unique chemical design of Cohera’s products can be formulated for use in a wide variety of surgical applications including plastic surgery, general surgery and orthopedic surgery.
Complexa, Inc.
Complexa is a pre-clinical biopharmaceutical company focused on the discovery and development of endogenous (naturally occurring) human pathway technology therapeutics for the treatment of inflammatory based and metabolic diseases, especially those involving the kidney.
Crystalplex Corporation
Crystalplex manufactures high-performance solid state lights and provides cutting-edge semiconductor nanocrystal technology to solid state lighting and display manufacturers.
CytoAgents
CytoAgents is focused on the development of innovative pharmaceutical products for the treatment of symptoms associated with Cytokine Release Syndrome (CRS), an overreaction of the immune system, commonly known as cytokine storm.
Emergence Dental
Emergence Dental is a research and development-stage medical device company taking a dental-first approach to emerging new regenerative products from metallic magnesium alloys, that safely resorb when implanted in the body.
Endolumik
Endolumik is a surgical device company that strives to advance the standard of care in minimally invasive, laparoscopic surgeries. Through introducing new tools in fluorescent guided surgery, we hope to make these procedures safer, more consistent, and drive better outcomes for patients.
Forest Devices
Stroke is the #1 cause of disability in the world with every 40 seconds someone in the US suffering a stroke. Stroke is devastating as it is a loss of oxygen to the brain, meaning delays in treatment dramatically worsen outcomes. Forest Devices has developed a device that offers faster, earlier identification of stroke in any environment. Currently in clinical trials, this is the team that is going to fundamentally change how the world views stroke.
FutureDerm, Inc.
FutureDerm approaches beauty from a scientific perspective and utilizes technology to provide unique, innovative, and effective products, analyses, and user interfaces.
Gus Gear, LLC.
Gus Gear’s flagship product, the Central Line Vest, was designed to keep Gus’s line locked down and secure, not only from accidental pulls but also from his wandering fingers. This comfortable vest covers and secures single, double, or multiple lumen central lines, eliminating the trauma from line pulls while allowing the wearer to be as active and independent as possible without undue fear of damaging their line.
Hability
Hability is the Patient Relationship Management platform for outpatient medicine, supporting patient follow-up over the phone, text, and email. Medical professionals use Hability to improve communication with patients between visits to the clinic, helping to form strong and lasting relationships between patients and providers. By supporting these relationships, Hability is helping practitioners treat more patients, helping patients heal better from injuries and illness, and making medicine personal again.
Hale Therapeutics
Hale Therapeutics is on a mission to end one of the leading causes of preventable death; smoking. Through their consumer-facing device, they’ve combined smoking cessation science with an elegant full-stack solution to wean people off of nicotine. Hale’s connected medical vaporizer automatically and gradually reduces nicotine intake over time, helping people achieve their goals of quitting smoking better than current Nicotine Replacement Therapies.
Health Monitoring Systems, Inc.
Health Monitoring Systems is a pioneer in community health surveillance. The company maintains online networks to collect data from hospitals and other healthcare providers, and then offers analytics of the aggregated information to detect, pinpoint and understand real-time and emerging health and safety issues. Clients include public health authorities, hospitals and others in the healthcare industry.
Immunetrics, Inc.
Immunetrics is a bio-simulation company, founded in 2001, that specializes in in silico disease modeling. Immunetrics modeling technology provides critical information to drug developers to accelerate and improve the drug discovery and development process, particularly in the identification of clinically relevant biomarkers. Immunetrics has developed a predictive software model of the human response to inflammation and coagulation, which enables drug discovery and development firms to gain comprehensive insights into a compound before investing significant resources into time-intensive and costly animal testing and human clinical trials.
Impact Protemics
Makes sample preparation tools that ensure every workflow starts with a high quality sample, allowing researchers to obtain useful data faster with higher statistical confidence, and ultimately accelerate time to market for high impact therapies, drugs and diagnostic tool.
June Brain, Inc.
June Brain is providing a telehealth eye-scanning solution that allows providers to identify new disease activity outside of the clinic for the more than 500 million individuals worldwide suffering from retinal and neurological disease.
Knopp Biosciences LLC
KNOPP BIOSCIENCES is a drug discovery and development company focused on delivering breakthrough treatments in neurological disorders through innovation, experience and partnership. Knopp’s lead compound, KNS-760704 (dexpramipexole), is currently in late-stage clinical development for amyotrophic lateral sclerosis, with additional indications under investigation.
Lumis Corp
Lumis is a cutting-edge technology company that aims to disrupt the traditional clinical and healthcare training experience by making it more immersive, accessible, and efficient. Our augmented reality and data-driven InSight Platform provides training across the healthcare education spectrum to ensure that the same quality of training can be received by anyone, at any time, and anywhere.
medSage Technologies, LLC (acquired by Philips Respironics)
medSage Technologies provides software and services which enable providers in the rapidly growing Home Medical Equipment (HME) industry to dramatically increase supply revenue from current patients by identifying those who require replacement supplies as soon as they are eligible. medSage also significantly improves quality of care by identifying patients who have problems in need of clinical attention. The underlying technology is fully developed and is presently being used by more than 120 customers and almost 600,000 of their patients.
MindTrace
MindTrace is developing technology that allows neurosurgeons to remove brain tumors and seizure-generating tissue, while ensuring each patient leaves the hospital the same person they were when they arrived, preserving personality and skills.
Mobile Aspects, Inc.
Mobile Aspects provides advanced item level tracking, inventory and accountability applications using Radio Frequency (RFID) technology for the healthcare delivery arena. Their initial product, InviRT (Inventory in Real Time) provides healthcare delivery organizations with real time transparency into the location, inventory level, and the last person to move their valuable supplies and medications at all times. The Healthcare Industry has been under increasing pressure to reduce errors in their processes, which cost the industry in excess of $50 Billion per year. Further, the entire industry is being encouraged by HMO’s and the government to significantly reduce costs, while, at the same time, improving security and accountability for high-cost, high-sensitivity items. Mobile Aspects partners with hardware suppliers, enterprise database vendors, and equipment supply companies to provide healthcare delivery organizations with an item tracking solution that monitors each item’s movement from supply room to end use. This helps health organizations to be more efficient, eliminate costly errors, and provide employee accountability.
Naima Health
Naima Health is an interdisciplinary team developing the MyHealthyPregnancy app which uses decision science, machine learning, and maternal-fetal health expertise to help pregnant women minimize their risk of adverse outcomes — including preterm birth.
Ocugenix
Ocugenix is developing therapies for angio-fibrotic diseases of the eye such as wet macular degeneration and diabetic retinopathy. These diseases are caused by an aberrant wound response in the back of the eye. Ocugenix’s compound triggers the process of wound resolution to cause the regression of the excessive fibrosis and vasculature recruited to heal the wound. The ability to cause regression of the pathological vessels and fibrosis in AMD and DR offers the patient the best hope of restoring lost sight.
Parcel Health
Parcel Health creates innovative and sustainable medication packaging. More than eight billion plastic prescription bottles are used annually in the United States, most ending up in landfills. Parcel Health provides eco-friendly medication packaging that is designed to be child-resistant and elderly-friendly, all while improving pharmacy workflows and reducing medication errors.
PECA Labs
PECA Labs is a Carnegie Mellon and UPMC spin-off dedicated to bringing better medical devices to orphan populations, with an initial focus on the pediatric cardiovascular system. Our first product, the MASA Valve, is a novel synthetic heart valve for a rare pediatric cardiac reconstructive procedure. The MASA Valve has already received Humanitarian Use Device (HUD) designation from the FDA, and 70 human implantations of the intra-operatively constructed version have shown improved freedom from re-operation compared to any currently available option.
PHRQL
PHRQL (pronounced freckle) is a software development firm that creates enterprise-level electronic health record (EHR) systems for medical nutrition therapy (MNT) coupled with shopper marketing and analytics capabilities. Our Connect & Coach™ solution provides an effective tool for supermarket dietitians while ensuring customers’ health data is protected and secure.
PredxBio
PredxBio is a Pittsburgh, PA-based scaling-stage company focused on the development of explainable AI-powered spatial analytics software platforms to decipher the complex cancer biology and bend the survival curve for immunotherapy cancer patients. PredxBio’s solutions empower clinicians/researchers to accelerate drug discovery, optimize clinical trials, advance companion diagnostics, personalize therapeutic options, and improve clinical workflows. PredxBio has already completed engagements with early paying customers including pharma partners who are harnessing PredxBio’s solutions to assess treatment response in immunotherapy.
Push2Spin
Push2Spin is a company dedicated to the development and commercialization of disruptive technologies
to revolutionize the global soft tissue grafting market.
Push2Spin allows for aspiration of fat from liposuction and prepares the fat to be reinjected right back
into the patient…in minutes.
Qualaris Healthcare Solutions, Inc.
Qualaris Healthcare Solutions, Inc. is a health information technology company whose software helps hospitals to improve patient satisfaction and reduce hospital acquired conditions, such as infections, falls, and other adverse events through observation-based auditing on best practices in patient safety, analyzing enterprise compliance data, and driving improvement with communication tools. Their offering will be sold via an SaaS model.
RC21X
RC21X is an advanced web-based system for measuring and monitoring brain performance capabilities. The core product uses fun, game-like experiences that encourage repeated use across a person’s lifespan. RC21X is a “web-ified” version of tests and apparatuses widely used to measure neurocognitive and neuromotor performance. The tool delivers self-administered brain health checkups in about 12 minutes—either in a home or office setting.
RedPath Integrated Pathology, Inc. (Acquired by PDI Inc.)
RedPath is a genomics-based cancer diagnostic company that provides comprehensive molecular analysis to resolve challenging diagnostic dilemmas. The company’s CLIA licensed, CAP certified laboratory delivers actionable diagnostic information that enables physicians to make personalized, effective treatment decisions for their patients.
Rimsys
Rimsys is a world-leading Regulatory Information Management (RIM) software for medical technology companies that digitizes, automates, and creates regulatory order. The only holistic RIM software for medical devices, in-vitro diagnostics, and medical device software, Rimsys makes it easy to navigate the pillars of regulatory affairs, including product registration, standards management, essential principles/GSPR, and regulatory intelligence. Rimsys is a holistic platform built by and for regulatory affairs professionals to efficiently ensure that products adhere to changing global regulations.
Rinovum Women’s Health, Inc.
Rinovum is an early-stage medical device company focused on reproductive health to aid in natural fertility and conception in the privacy of the patient’s home.
Sharp Edge Labs, Inc.
Sharp Edge Labs is an assay development company delivering better assays for studying cell-surface proteins. The company’s patenteTargeted Sensor technology provides a more accurate and detailed picture of protein trafficking, a process that is critical to the biology of the largest class of pharmaceutical drug targets (GPCRs, Ion Channels and Transporters). The company offers reagents and kits, assays and cell-lines, and assay services including development of new assays for proprietary targets.
sovaSage
The sovaSage TherapistAssist software product was designed specifically for Sleep Labs and Durable Medical Equipment (DME) providers. The result is an unequaled product in the treatment of sleep apnea.
SpectraGenetics LLC
SpectraGenetics is an innovative gene tagging company providing proprietary and breakthrough technologies for drug discovery and development. These technologies allow researchers to accurately determine when a gene is expressed and to visualize in real time the expression, cellular localization or activation of proteins in living cells. This information has the potential to transform the drug discovery and development process by providing significant productivity improvements in identifying suitable targets and leads for therapeutic development.
Spoken
Spoken helps people with aphasia or other language disorders speak again by predicting likely words and phrases. The company has taken the same machine learning algorithms that power a phone’s autocomplete function and applied them to much bigger data, giving suggestions that fit the context and improve with time. It’s a radically different approach to treating disabilities that aims to serve a growing global market.
STARR Life Sciences Corp.
STARR Life Sciences’ mission is to improve the efficacy of medical research by creating small-animal versions of human medical diagnostic and monitoring devices. These parallel tools ensure that medical research results, obtained using mice and rats, improve the health of humans. STARR’s cornerstone product, the MouseOx(TM), is the world’s first and only pulse oximeter for mice and rats. The MouseOx is more than just a pulse oximeter. It provides real-time measurements of pulse rate, blood flow, arterial oxygen saturation, breath rate and effort to breath all from one simple, easy to use, non-invasive sensor.
Sterile Vision
Sterile Vision’s goal is to help build the operating room of the future. In today’s operating room, there is large variability among procedures and surgeon preferences that make organization and tracking of the surgical instruments a cumbersome task. This leads to operating room processes that are prone to missing instruments, excessively large trays and workflow inefficiency.
At Sterile Vision, we offer the solution via use of computer vision to accurately track surgical instruments inside and outside the operating room. Hands-free tracking will lead to reduction of lost instruments, optimization of large instrument trays, increased OR efficiency, and decreased costs.
Telling.AI
Telling.ai analyzes voice and breath sounds to assess lung health.
Thar Pharmaceuticals, Inc. (acquired by Grünenthal)
Thar Pharmaceuticals reinvents known, safe, on-the-market drugs by improving their clinical performance and economic benefits. We focus on transforming intravenous (IV) drugs into orally administered drugs, thus eliminating the cost of IV drug administration, a $34 billion annual worldwide healthcare cost paid by health systems, patients and insurers.
ThoroughCare
ThoroughCare’s intuitive software gives practices of all sizes the right tools to effectively manage Medicare’s profitable reimbursement programs such as CCM, AWV and more.
Treatspace
Treatspace builds and installs software systems that power secure health networks for medical practices, hospitals, medical-related organizations. Market growth for Treatspace health networks is driven by ACA, HITECH and HIPAA legislation. As hospitals rapidly acquire physician practices, they must grow patient volume, maximize reimbursement and prevent both penalties and referral leakage within the system to remain competitive. Treatspace networks operate standalone or atop legacy systems.